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Lowest Net Cost Formulary Update Bulletin

May 13, 2025
Pharmacy update image

The changes in this update apply to all groups that use OptumRx

The majority of these changes include decisions that occurred as a result of our February 2025 Pharmacy and Therapeutics Committee (P&T) meeting. Members negatively impacted by one of these changes will be sent a letter this month.

FORMULARY UPDATES

Additions
These drugs will be added to the formulary effective July 1, 2025.

ProductDrug Class/CategoryUtilization Management ProgramsFormulary Status
LazcluzeCancerPA/QLNon-Preferred Specialty
LivdelziPrimary Biliary CholangitisPA/QLNon-Preferred Specialty
MiplyffaNiemann-PickPA/QLNon-Preferred Specialty
NemluvioPrurigo Nodularis/
Atopic Dermatitis
PA/QLPreferred Specialty
TeriparatideOsteoporosisPAGeneric Specialty
VafseoCKD-related anemiaPA/QLNon-Preferred Specialty
VoranigoCancerPA/QLNon-Preferred Specialty

Stelara Biosimilars Coverage Update

Beginning July 1, 2025, Stelara (brand) will be removed from the Lowest Net Cost formulary. The biosimilars  Yesintek and Selarsdi will instead be the preferred products.

Members using brand Stelara will be notified and supported through their transition to a preferred product. Additionally, providers will be notified of these formulary changes prior to implementation to ensure a seamless transition.

This biosimilar strategy provides continued quality of care for patients, guaranteed supply, availability of all strengths, and affordability for patients, including manufacturer copay assistance programs and significant cost reduction for plan sponsors.

Medical Benefit Only

Beginning July 1, 2025, the specialty drugs NIKTIMVO and TECELRA will be eligible for coverage under the medical benefit only. Note: generics of these medications will be on formulary.

Moving to Nonformulary Status

FORTEO and VICTOZA will move to nonformulary status effective July 1, 2025.